AMPK: Lessons from transgenic and knockout animals

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AMPK: Lessons from transgenic and knockout animals.

AMP-activated protein kinase (AMPK), a phylogenetically conserved serine/threonine protein kinase, has been proposed to function as a fuel gauge to monitor cellular energy status in response to nutritional environmental variations. AMPK system is a regulator of energy balance that, once activated by low energy status, switches on ATP-producing catabolic pathways (such as fatty acid oxidation an...

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ژورنال

عنوان ژورنال: Frontiers in Bioscience

سال: 2009

ISSN: 1093-9946,1093-4715

DOI: 10.2741/3229